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Kyowa Hakko Kirin to manufacture and supply for clinical, commercial use
September 4, 2013
By: Tim Wright
Editor-in-Chief, Contract Pharma
Ultragenyx Pharmaceutical has entered into a collaboration and license agreement with Kyowa Hakko Kirin Co., Ltd. (KHK), to develop and commercialize KRN23, a recombinant fully human monoclonal IgG1 antibody intended to treat X-linked hypophosphatemia (XLH). KHK is currently completing a Phase I/II study in adults with XLH in the U.S. and Canada. The two companies plan to initiate a pediatric XLH program in 2014. XLH is a rare metabolic bone disorder caused by excessive loss of phosphate in the ...
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